Patients were challenged with Ragweed pollen during the off season; and using extensive performance tests, were compared to non-challenged allergic rhinitis patients. The challenged patients showed evidence of decreased cognition, vigilance, response time, accuracy, memory, reasoning, calculating, and coordination. There was also increased sedation, drowsiness, and lethargy. Most patients with these effects were UNAWARE OF THESE EFFECTS.
Dr. Portner Says: The newer antihistamines may help, but in my experience more extensive treatment is needed such as nasal steroids, and or prevention of the release of the mediators by allergen immunotherapy.